Products

English name: Fluxapyroxad
CBNumber: CB00136613
Molecular formula: C18H12F5N3O
Molecular weight: 381.3
MOL File: 907204-31-3.mol
Boiling point: 428.4±45.0°C (Predicted)
Density: 1.42±0.1g/cm3 (Predicted)
Storage conditions: Store at -20°C
Solubility: DMSO: ≥100mg/mL (262.26mM)
Acidity coefficient (pKa): 11.73±0.70 (Predicted)
Form: Solid
Color: White to off-white
BRN:15702063
Henry’sLawConstant:3.3×106mol/(m3Pa)at25℃,Maniereetal. (2011)
Main applications: agriculture environmental InChI: InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26) Chemicalbook 17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H, 24,27)
InChIKey:SXSGXWCSHSVPGB-UHFFFAOYSA-N
SMILES: N1(C)C=C(C(NC2=CC=CC=C2C2=CC(F)=C(F)C(F)=C2)=O)C(C(F)F)=N1EPA Chemical substance information: 1H-Pyrazole-4-carboxamide,3-(difluoromethyl)-1-methyl-N-(3′,4′,5′-trifluororo[1, 1′-biphenyl]-2-yl)-(907204-31-3)
Amide-based fungicide
Fluxapyroxad is a patented product developed by BASF. It is an amide-based fungicide with excellent preventive and therapeutic activity. It can inhibit spore germination, mycelial growth, and spore formation, can control at least 26 types of fungal diseases, can be used on nearly a hundred crops, and is highly effective against various strains of triazole and methoxyacrylate resistant strains. When combined with triazole fungicides, it produces yield-increasing effects. Therefore, Fluxapyroxad has become the leading product in the global market for SDHI fungicides and a new hotspot in fungicide research and development.
Physical and chemical properties
Fluxapyroxad pure is a white crystal, with a melting point of 156.8°C, relative density of 1.42 (room temperature), and vapor pressure (25°C) > 8.1×10-9 Pa. Its solubility at room temperature (g/L, 2Chemicalbook 0°C): acetone > 250, acetonitrile 167.6±0.2, dichloromethane 146.1±0.3, ethyl acetate 123.3±0.2, methanol 53.4, toluene 20.0, n-octanol 4.69, n-heptane 0.106. The octanol/water partition coefficient (20°C) Kowlog P was 3.08 (deionized water), 3.09 (pH4), 3.13 (pH7), and 3.09 (pH9). At pH values of 4~9, Fluxapyroxad hydrolyzes stably, and no photolysis conversion occurs in natural water using artificial light (DT50 and quantum yield not included).
Mechanism of action
Fluxapyroxad is a succinate dehydrogenase inhibitor that acts on succinate dehydrogenase in the mitochondrial respiratory chain complex II, inhibiting its activity, thereby inhibiting pathogen spore germination as well as the growth of germ tubes and mycelium.
Efficacy and Effects
Fluxapyroxad belongs to the bifenpyroxamide class of fungicides characterized by high efficiency, broad-spectrum activity, long-lasting effect, and strong selectivity. It has excellent systemic conductivity and preventive and therapeutic effects. It is rain-resistant and effective, and through foliar and seed treatments, it effectively controls major diseases affecting grains, soybeans, corn, rapeseed, fruit trees, vegetables, sugar beets, peanuts, cotton, turf, and specialty crops. Its control effect is better than triazole fungicides and more effective than methoxypropylene acid-ester fungicides, providing better protection, relatively safe to use, and less likely to cause phytotoxicity.
How to use
Prevention and control of rice sheath blight: For the first application before or early onset at the end of tillering in rice, 300 g/L Fluxapyroxid suspension agent can be evenly sprayed on the leaves, with a dosage of 20-30 ml per mu. Depending on the disease incidence, apply the second application during booting. The safety interval for rice is 21 days, with a maximum of two applications per season.